Abstract Both exogenous and endogenous cannabinoids can allosterically modulate glycine receptors (GlyRs). However, little is known about the molecular basis of cannabinoid-GlyR interactions. Here we report that sustained incubation with the endocannabinoid anandamide (AEA) substantially increased the amplitude of glycine-activated current in both rat cultured spinal neurons and in HEK-293 cells expressing human ?1, rat […]

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A Vancouver man will appear in Federal Court on Tuesday arguing for an exemption to the drug laws because they infringe on his constitutional freedom of religion to smoke his sacred weed – marijuana. Find out more about the case (including when and where to attend the proceedings). With Insite attendees allowed to inject illicit […]

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I’m feeling the same way.  It’s very telling when you have the issue under your microscope for an extended time.  On the upside, this prohibition is under attack from many directions now, more than ever in history, and more people are open to learning about it every hour.  From industrial hemp to medical cannabis to […]

nytimes.com: THREE and a half years ago, on my 62nd birthday, doctors discovered a mass on my pancreas. It turned out to be Stage 3 pancreatic cancer. I was told I would be dead in four to six months. Today I am in that rare coterie of people who have survived this long with the […]

nytimes.com: THREE and a half years ago, on my 62nd birthday, doctors discovered a mass on my pancreas. It turned out to be Stage 3 pancreatic cancer. I was told I would be dead in four to six months. Today I am in that rare coterie of people who have survived this long with the […]

MILWAUKEE – One prominent Milwaukee couple is making a pitch in a documentary to not only legalize marijuana but to turn it into a cash crop grown in Milwaukee. Their argument: America has spawned a criminal class by prosecuting pot users, creating a hopeless cycle of poverty. They…read more at http://www.wisn.com/news/south-east-wisconsin/milwaukee/Prominent-Milwaukee-couple-proposes-legalizing-marijuana/-/10148890/13421380/-/mrms6n/-/index.html

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