Cannabinoids

CB1 and CB2 structures. cannabinoid receptor 1 (brain) NMR solution structure of a peptide mimetic of the fourth cytoplasmic loop of the CB1 cannabinoid receptor based on the PDB 2b0ycoordinates. Identifiers Symbol CNR1 Alt. symbols CNR Entrez 1268 HUGO 2159 OMIM 114610 RefSeq

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New track. Part of a forthcoming chillout LP on 96Hz Records. Would love some fresh ears on this if you have time. Comments much appreciated. Thanks for listening! …read more at http://www.idmforums.com/showthread.php?t=112033

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Raphael Mechoulam is an Israeli professor for Medicinal Chemistry and Natural Products at the Hebrew University of Jerusalem. While working on research at the Weizmann Institute of Science in 1964, Michoulam succeeded in the isolation, structure elucidation and total synthesis of delta9-tetrahydrocannabinol, the main active principle of cannabis. In this video he talks about the […]

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A paper in the October issue of the Journal of Psychopharmacology will be of interest to my readership. It looks at the consequences of exposure to an exogenous cannabinoid agonist Byrnes JJ, Johnson NL, Schenk ME, Byrnes EM. Cannabinoid exposure in adolescent female rats induces transgenerational effects on morphine conditioned place preference in male offspring.J […]

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Various drugs of abuse have effects on our brains because they resemble the neurotransmitters that our brains produce. For example Endorphines and Enkephalins resemble exogenous morphine or heroin, Endogenous Anandamide resembles marijuana, acethylcholine resembles nicotine and cocaine/amphetamines resemble dopamine, etc. The endogenous cannabinoid signaling (ECS) is a complex endogenous signaling system comprised of Cannabinoid receptors […]

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Rmaceutical Inc., parents companies regarding Astellas, as executive vice president. Clash appealing Yutaka Yanagita, Ph.D., is surely an worker associated with Astellas Pharmaceutical Corporation. Toichi Takenaka, DVM, Doctor of philosophy, a senior technology advisor and also former Chairman involving Astellas Pharma Corporation. The conventional Ans Tze for that treatment method Vismodegib 879085-55-9 involving serious leukemia […]

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The oral administration of the non-psychotropic cannabis plant constituent cannabidiol (CBD) is safe and well tolerated in humans, according to clinical trial data published online by the journal Current Pharmaceutical Design. Investigators at Kings College in London assessed the physiological and behavioral effects of CBD and THC versus placebo in 16 healthy volunteers in a […]

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Examination showed low density of cannabinoid receptors in the hypothalamus—meizitang botanical slimming soft gel  It is necessary to go on dieting after obese people who have reduced certain weight by taking meizitang.  Obesity as a global problem, has attracted wide attention. Cannabinoid receptors 1 and obesity “. Obesity has become a worldwide epidemic, serious harm […]

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Unfortunately, synthetic drugs are a very serious problem in all of our military services, and the military’s use of urinalysis will not catch them all. The military tests for drugs regularly, therefore, soldiers wishing to attain a negative drug-test result often turn to synthetic drugs. Synthetic drugs are much more dangerous than the plant-based drugs they […]

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(NORML) The oral administration of the non-psychotropic cannabis plant constituent cannabidiol (CBD) is safe and well tolerated in humans, according to clinical trial data published online by the journal Current Pharmaceutical Design. Investigators at Kings College in London assessed the physiological and behavioral effects of CBD and THC versus placebo in 16 healthy volunteers in a randomized, double-blind, crossover trial. […]

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Journal of Forensic Sciences, 2012, Early View DOI: 10.1111/j.1556-4029.2012.02261.x CP 47,497, a potent cannabinoid receptor type 1 agonist, is the main active ingredient in the herbal mixture “Spice” sold in European countries. The illegal use of “Spice” for its psychoactive effects has become a social issue. In this study, the in vitro metabolism of CP 47,497 […]

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<!– Study: Non-Psychotropic Cannabinoid Proven To Be Safe In Humans –> by Paul Armentano, NORML Deputy Director September 5, 2012 The oral administration of the non-psychotropic cannabis plant constituent cannabidiol (CBD) is safe and well tolerated in humans, according to clinical trial data published online by the journal Current Pharmaceutical Design. Investigators at Kings College […]

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Abstract BACKGROUND: Cannabinoid receptor agonists reverse nausea and vomiting produced by chemotherapy and radiation therapy in animals and humans but have not been tested against opioid-induced emesis. This study tests the hypothesis that cannabinoid receptor agonists will prevent opioid-induced vomiting. METHODS: Twelve male ferrets were used. They weighed 1.2-1.6 kg at the beginning and 1.8-2.3 […]

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